Mediherb Andrographis Complex

Mediherb Andrographis Complex

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60 Tablets
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MediHerb Andrographis Complex

Andrographis Complex contains a blend of herbs to support normal immune function. Andrographis, Echinacea angustifolia root, Echinacea purpurea root and Holy Basil provide a unique range of phytochemicals including diterpenoid lactones (collectively referred to as andrographolide), flavonoids, alkylamides, caffeic acid derivatives (cichoric acid, echinacoside and cynarin), essential oil (rich in monoterpenes and sesquiterpenes, typically eugenol) and polyphenols. The blending of E. angustifolia and E. purpurea roots ensures that a spectrum of constituents (especially the alkylamides) are present in the optimal form and quantity for immune enhancement. This tablet contains herbs with standardised levels of key phytochemicals to ensure optimal strength and quality: 50 mg of andrographolide and 2.0 mg of alkylamides per tablet

Mode of Action

Andrographis has been traditionally used for relief of influenza, cough and sore throat, it also is a bitter, diaphoretic and liver tonic. Andrographis extracts standardised for andrographolide may relieve the symptoms of uncomplicated upper respiratory tract infection. This product contains a mixture of alkylamides, a class of Echinacea compounds which are constituents identified as bioavailable (present in plasma after ingestion) as demonstrated in a human phase I trial. These alkylamides have exhibited nonspecific immune-enhancing activity in a human clinical trial, which may help reduce the incidence of winter colds. Holy Basil has been used traditionally as a tonic and for relief of common cold, fever, influenza and sinusitis.

MediHerb Andrographis Complex Indications

  • When taken soon after exposure, or at the first sign of symptoms may provide support for and relief of the symptoms of colds, influenza and mild upper respiratory infections.
  • Relief of the fever of influenza.
  • Relief of mucous congestion.
  • Aids digestion.
  • Tonic to support the liver.

Contraindications and Cautions

Contraindicated in pregnancy. Echinacea is contraindicated in patients taking immunosuppressant medication (eg transplant patients). Short-term therapy only is suggested in this instance. Caution is advised in patients receiving midazolam by injection. The risk of allergic reaction to Echinacea is very small, especially when preparations of the root is used (as these are free of pollen). Caution is advised in patients receiving midazolam by injection. Discontinue 7 days prior to general anaesthesia.   

Each MediHerb Andrographis Complex tablet contains:

  • Andrographis paniculata (Andrographis) extract equivalent to dry leaf
    • standardised to contain andrographolide 50 mg 2.0 g
  • Ocimum tenuiflorum (Holy Basil) extract equivalent to dry herb 500 mg
  • Echinacea purpurea (Echinacea) extract equivalent to dry root 300 mg
  • Echinacea angustifolia (Echinacea) extract equivalent to dry root 200 mg
    • containing alkylamides 2.0 mg from both Echinacea extracts
  • Ocimum tenuiflorum (Holy Basil) leaf essential oil 10 mg

Dosage and Administration

Adults: 1 tablet 2-4 times daily. Dosage can be increased to 6 tablets daily temporarily for acute conditions.
Children 6-12 years: 1 tablet 1-2 times daily.

Additional Therapy

  • For further immune support combine with Echinacea Premium tablets or liquid extract or Zinc Protect tablets.
  • For relief of symptoms associated with dry, sore throats consider Herbal Throat Spray.
  • Consider DiaCo Phytosynergist™ liquid to enhance diaphoresis during acute respiratory infections.
  • Combine with Poly-C Powder to help reduce severity and duration of mild infections.
  • For additional relief of the symptoms of upper respiratory catarrh, hay fever and sinusitis consider Eyebright Complex tablets.

The Important Constituents

Echinacea is the most widely used herb and the most misunderstood. MediHerb has over many years, invested heavily into research on Echinacea. The levels of the phenolic acid esters, eg echinacoside, are commonly used as marker compounds or indicators of Echinacea quality. However, with recent trials highlighting the importance of alkylamides for clinical efficacy, it is important that quality products are characterised for these as well. This has led to the incorporation of a specification and analytical test methodology for Echinacea products in the USP NF-19 draft monographs which focuses on alkylamides tested by HPLC and DAD detection. The alkylamides being tested are the 2,4-dienoic alkylamides and the 2-enoic alkylamides.

This method has been adopted by MediHerb and the alkylamides are determined as 2,4-Diene alkylamides and 2-ene alkylamides; The 2-Enes are characteristic of Echinacea angustifolia and are not found in the other species, the 2,4- Dienes are found in both E. purpurea and E. angustifolia. The 2,4-Dienes are responsible for the intense tingling sensation in the mouth when tasting good quality Echinacea products.

The phenolic acids are determined as the levels of caftaric acid, echinacoside and cichoric acid; echinacoside is typical of E. angustifolia and E. pallida roots and is not found in E. purpurea. Cichoric acid is not found in E. angustifolia root, but is found in the aerial parts of all species and characteristically in the root of E. purpurea.MediHerb products are quantified to contain a minimum level of alkylamides by the USP-NF19 HPLC method, the levels of phenolic acids are measured for information only and are used to confirm product identity and the absence of contamination from other Echinacea species.

The MediHerb Difference

MediHerb has gained significant experience in the manufacture and testing of Echinacea products over the past 15 years. This includes a 3 year PhD study, extensive analytical method development, development of harvesting, drying and storage protocols to maximise retention of actives and a successful clinical trial.

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