Orthoplex BACE 2000
Indications
May assist with conditions associated with:
- Oxidative stress (e.g. ageing, poor immunity)
- Detoxification
Gluten Free
Glucose Free
Lactose Free
Vegetarian
Excipients
Calcium hydrogen phosphate, povidone, crospovidone, microcrystalline cellulose,
magnesium stearate, hypromellose, macrogol 400, silicon dioxide, iron oxide red
77491, carnuaba wax, vanillin.
Orthoplex BACE 2000 Interactions
Take two hours away from antibiotic medications,
as minerals such as zinc and manganese may reduce
absorption of antibiotics.
Synergistic Formulae
Cytogammon 50
DHA/EPA
LM1
Dosage
1 tablet twice daily after meals, or as prescribed
Each tablet of Orthoplex BACE 2000 contains:
| |
25 μg |
|
(equiv. selenium 10 μg) |
|
|
Allium sativum (garlic bulb, dry) |
10 mg |
|
Ascorbic acid (vitamin C) |
125 mg |
|
Betacarotene |
1.5 mg |
|
Calcium pantothenate (vitamin B5) |
125 mg |
|
(equiv. pantothenic acid 114.5mg) |
|
|
Citrus bioflavonoids extract |
50 mg |
|
Cysteine hydrochloride |
50 mg |
|
d-alpha tocopheryl acid succinate (vitamin
E) |
75 mg |
|
Lipoic acid |
20 mg |
|
Manganese amino acid chelate |
10 mg |
|
(equiv. manganese 1mg) |
|
|
Nicotinamide (vitamin B3) |
10 mg |
|
Pyridoxine hydrochloride (vitamin B6) |
25 mg |
|
R,S alpha lipoic acid |
20 mg |
|
Retinyl palmitate (vitamin A) |
1000 IU |
|
Riboflavin 5-phosphate (vitamin B2) |
10 mg |
|
Zinc amino acid chelate |
40 mg |
|
(equiv. zinc 8mg) |
|
TECHNICAL INFORMATION
BACE 2000 contains a combination of nutrients known for their antioxidant
properties. Studies show that antioxidants work better in the body when taken in
combination.
Oxidative Stress
When oxygen is acted upon by environmental agents or catalysts such as
radiation, drugs, air pollutants and toxic gases or even when used by the human
body in some enzyme reactions, highly reactive by-products called oxygen free
radicals can be produced. Two of these free radicals are particularly potent,
superoxide (02) and hydroxyl radical (OH). These free radicals, along with
others, can cause destruction to cell membranes within the body.
Many body mechanisms and reactions produce free radicals, particularly the
body's detoxification processes. Phase I liver detoxification results in the
production of many free radicals and other toxic metabolites. Many cellular
components of the immune system, particularly the neutrophils, produce
oxygenated free radicals to kill foreign bacteria. To keep the system in
balance, the antioxidant enzyme system mops up excessive free radicals to
prevent the destruction of human cells after the bactericidal event is complete.
Inflammation also produces free radicals, indicating a need for antioxidants in
inflammatory disorders. Ageing is associated with free radical damage. All of
these situations therefore, may require extra antioxidant support.
Lipoic acid is a water and fat soluble antioxidant, which enables it to work
both inside the cell and in the intracellular spaces. It is effective against
the hydroxyl, hypochlorous acid and single oxygen free radicals.[1-3] In the
body it is converted to dihydrolipoic acid, thus allowing it also to scavenge
peroxyl and other types of free radicals. It extends the life of other
antioxidants such as vitamin C and glutathione and helps recycle vitamin E, so
that they can continue to provide protection against free radical damage.[4] It
also acts as a metal chelator particularly of Hg2+, Cd2+, Cu2+ and Fe2+, i.e. it
is a metal chelating antioxidant.[5-7]
Selenium is classified as essential for the health of humans because of its
role as a component in glutathione peroxidase.
Glutathione peroxidase and vitamin E both play a role in the detoxification
of peroxides and free radicals. Selenium also may protect against peroxynitrite
radicals.[8]
Vitamin E is a naturally occurring antioxidant and specifically protects
unsaturated fatty acids from oxidative damage. Any plant that has high levels of
polyunsaturated fatty acids, (sunflower seeds, wheat germ and soya beans) always
contains a high amount of vitamin E. In animals, vitamin E is found bound to the
cell membrane. Vitamin E, Lipoic acid and the Glutathione peroxidase enzyme
system act synergistically to protect the cell membrane.
Vitamin A and β-carotene - both have antioxidant
functions. β-carotene, the precursor of vitamin A, has
unique antioxidant properties. As a fat-soluble antioxidant,
β-carotene scavenges singlet oxygen[9] and decreases lipid peroxidation.[10]
Vitamin A and vitamin E both interact as fat-soluble antioxidants.
Cysteine is a sulphur-containing amino acid. It helps to build the structure
of the glutathione peroxidase enzyme system. Increased levels of cysteine
stimulate the glutathione peroxidase system as well as glutathione synthesis.
