Orthoplex Lymphodran
Excipients
Calcium hydrogen phosphate, crospovidone, silicon dioxide, magnesium stearate,
hypromellose, macrogol 400, carnauba wax, acacia.
Pack size
50 tablets
Dosage
1 tablet three times daily, or as prescribed.
Indications
Orthoplex Lymphodran may assist with conditions associated with:
* Inflammation
* Viral infections
* Oedema
Interactions
N/A
Contraindications
N/A
Each tablet of Orthoplex Lymphodran contains:
|
Ascorbic acid (vitamin C) |
50 mg |
|
Quercetin |
200 mg |
|
Rutin |
500 mg |
TECHNICAL INFORMATION
Inflammation, oxidative stress and immune dysfunction underlie many health
disorders and disease states. It is fundamental to address these processes in
order to maximise your patient's health potential. Studies have supported the
use of quercetin and rutin to down regulate inflammation, reduce oxidative
stress, modulate viral activity and to support immune health and wound healing
processes.
Inflammation
Many substances have been researched for their anti-inflammatory effect; one of
the most potent of the natural substances is quercetin. Quercetin down regulates
a number of inflammatory mediators including Cyclooxygenase[3] and
Lipoxygenase[4] pathways; NF-kappa B;[5] Tumour Necrosis Factor alpha;[6]
Prostaglandin E2;[7] Series 4 Leukotrienes[8] and Histamine.
Like quercetin, rutin has shown to help support
inflammatory processes. It has been suggested that rutin may play a more
specific role in chronic inflammatory processes.[10]
Viral Infections
In vitro studies show quercetin possesses antiviral properties. A study
conducted on Herpes simplex type 1, polio-virus type 1, parainfluenza virus type
3 (Pf-3), and respiratory syncytial virus (RSV) found that quercetin caused a
concentration-dependent reduction in the infectivity of each virus. In addition,
it reduced intracellular replication of each virus.
Apoptosis
Quercetin has also been shown to upregulate apoptosis (healthy programmed cell
death) and down regulate mitosis (cell division) thus having a direct effect on
cancer cell growth and development. Due to its ability to upregulate apoptosis,
quercetin has also shown promising benefit as support therapy during
chemotherapy.[
